Deborah A. Lannigan, Ph.D.
Professor of Pathology, Microbiology and Immunology
      
        Associate Professor of Biomedical Engineering
      
        712 Preston Research Building
      
            2220 Pierce Ave
      
            Nashville
      
            Tennessee
      
            37232-6840
      
      (615) 322-4560
      
      More Information
Signaling pathways involved in mammary gland homeostasis and breast cancer
Research Information
My laboratory focuses on signaling pathways that are involved in mammary gland homeostasis and breast cancer. Cancer cells frequently hijack pathways used during development. Therefore, by studying normal organogenesis it is possible to identify novel therapeutic opportunities for the treatment of breast cancer. To facilitate these studies we have developed a novel organotypic model system using living normal breast and breast cancer tissue. Additionally, we are developing a drug that we are trying to transition to the clinic for the treatment of metastatic breast cancer.
 
